Table 1. Hematopoiesis- and Iron-related Characteristics of NHD13 mice.
| RBC count | Hb | MCV | Retic count | WBC count | Platelet count | Serum EPO | Bone marrow cells | Liver iron concentration | |
|---|---|---|---|---|---|---|---|---|---|
| (units) | (106 /μL) | (g/dL) | (fL) | (106 /μL) | (106 /μL) | (103 /μL) | (μg/μL) | (107 cells) | (mg/g dry weight) |
| WT | 10±0.1 | 14.7±0.1 | 50±0.5 | 495±67 | 5.5±0.6 | 759±67 | 308±48 | 12.4±0.7 | 0.23±0.07 |
| MDS | 6.73±0.29 | 11.2±0.4 | 60±1.3 | 440±30 | 3.0±0.4 | 672±80 | 4832±1,154 | 15±0.8 | 0.51±0.04 |
| *** | *** | *** | NS | ** | NS | *** | * | * |
WT = wild type; MDS = myelodysplastic syndrome (NHD13) mice; RBC = red blood cell; Hb = hemoglobin; MCV = mean corpuscular hemoglobin; Retic = reticulocyte; WBC = white blood cell; EPO = erythropoietin; NS = not significant; * P<0.05; ** P<0.01; *** P<0.0001.