Table 5.
S. no. | Inhibitor/drug | Mechanism/effect | Clinical progress | References |
---|---|---|---|---|
1 | Eleuquin (EL246) | Cell adhesion inhibitor | Under predevelopment by LigoCyte | [185] |
| ||||
2 | BIBW 2948 | EGFR internalization reducer | 4 Weeks treatment (NCT00423137) | [186] |
| ||||
3 | Bosentan | Endothelin receptor inhibitor | 18 Months treatment (NCT02093195) | [187, 188] |
| ||||
4 | Solithromycin | Macrolide antibiotic | Early termination of the trial (NCT02628769) | [189] |
| ||||
5 | Thiazolidinediones | PPARγ agonists | 10 Months treatment (NCT00103922) |
[190, 191] |