Table 3.
The effect of minnelide on serum-steroid and gonadotropin in female mice
P (ng/mL) | E2 (pg/mL) | FSH (mIU/mL) | LH (mIU/mL) | |
---|---|---|---|---|
Control | 22.59 ± 4.05 | 67.24 ± 9.36 | 86.73 ± 18.35 | 28.73 ± 2.30 |
100 μg/kg day | 23.65 ± 2.06 | 51.21 ± 7.18 | 85.62 ± 24.19 | 30.28 ± 4.81 |
200 μg/kg day | 17.30 ± 4.11 | 50.36 ± 6.30 | 75.55 ± 13.60 | 28.92 ± 6.09 |
400 μg/kg day | 15.06 ± 4.06 | 43.30 ± 5.46** | 126.0 ± 10.75* | 34.54 ± 4.75* |
P, progesterone; E2, estradiol; FSH, follicle-stimulating hormone; LH, luteotropic hormone. Data were represented as mean ± SD; n = 5 per group. *P < 0.05 and **P < 0.01 versus control groups