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. 2023 Mar 31;195(12):7379–7396. doi: 10.1007/s12010-023-04333-z

Table 3.

The effect of minnelide on serum-steroid and gonadotropin in female mice

P (ng/mL) E2 (pg/mL) FSH (mIU/mL) LH (mIU/mL)
Control 22.59 ± 4.05 67.24 ± 9.36 86.73 ± 18.35 28.73 ± 2.30
100 μg/kg day 23.65 ± 2.06 51.21 ± 7.18 85.62 ± 24.19 30.28 ± 4.81
200 μg/kg day 17.30 ± 4.11 50.36 ± 6.30 75.55 ± 13.60 28.92 ± 6.09
400 μg/kg day 15.06 ± 4.06 43.30 ± 5.46** 126.0 ± 10.75* 34.54 ± 4.75*

P, progesterone; E2, estradiol; FSH, follicle-stimulating hormone; LH, luteotropic hormone. Data were represented as mean ± SD; n = 5 per group. *P < 0.05 and **P < 0.01 versus control groups