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Time course of mRNA and protein distribution in NHP dLN
(A) RNAscope EGFP labeling of NHP iliac LN out to 7 days post-mRNA-LNP i.m. injection. (B) EGFP staining of the iliac LN at 8, 24, 72, and 169 h post-i.m. injection. (C and D) Bubble plot of mRNA H-score (C) and percentage of EGFP positivity (D) comparing dLN versus non-dLN (mesenteric). Area shown in insets is indicated in the low-magnification images. Scale bars, 1 mm and 100 μm.
