Fig. 2.

Flow diagram of the study stratified by resectability status according to the National Comprehensive Cancer Network classification (borderline resectable or locally advanced), primary treatment (best supportive care, primary chemotherapy or upfront surgery) and first-line chemotherapy regimen (FOLFIRINOX, gemcitabine/nab-paclitaxel, gemcitabine, other)

Outcome of surgery is classified as resected or explored only. *Secondary CT performed in six patients before initiation of planned neoadjuvant chemotherapy showed distant metastasis, and the patients received palliative chemotherapy. ^†Two patients with borderline resectable pancreatic cancer underwent upfront surgery followed by adjuvant chemotherapy. One patient with borderline resectable pancreatic cancer received fluorouracil/leucovorin/oxaliplatin and underwent subsequent resection. CT, computed tomography; FOLFIRINOX, fluorouracil, leucovorin, oxaliplatin and irinotecan; GnP, gemcitabine nab-paclitaxel.