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. Author manuscript; available in PMC: 2023 Dec 29.
Published in final edited form as: Acta Biomater. 2020 Jul 6;113:267–278. doi: 10.1016/j.actbio.2020.07.002

Figure 4. Effects of EV/CCM/CCM-D treatment on elastic matrix deposition and crosslinking in EaRASMC cultures.

Figure 4.

(A) Total matrix elastin amounts in culture groups measured using a Fastin assay, shown normalized to cell content in the respective cultures. (B) Desmosine (elastin crosslinker) content in cultures shown normalized to total protein amounts in the respective cultures. (C) Matrix collagen content estimated by hydroxyproline (OH-Pro) assay. Values shown in plots indicate mean ± SE of measurements made in n = 6 replicate cultures per condition. * denotes p < 0.05 compared to TC cultures, # denotes p < 0.05 compared to EV treated samples, $ denotes p < 0.05 compared to CCM treated sample.