Table 1.
Summary statistics for the different groups of Ab-Ag complexes considered in the study. Fv antibodies are those that contain both VH and VL whereas the sdAbs contain a single variable domain derived from either heavy chain (VH) or light chain (VL).
| PDB files | Total atom-atom contacts | Unique paratope residues | Unique paratope atoms | Unique epitope residues | Unique epitope atoms | Mean resolution (Å) | |
|---|---|---|---|---|---|---|---|
| Total | 1833 | 856751 | 41643 | 196315 | 35812 | 173940 | 2.2 |
| Protein-binding Fv | 1058 | 515651 | 25414 | 118046 | 23347 | 110083 | 2.2 |
| Peptide-binding Fv | 367 | 151799 | 7981 | 37494 | 3474 | 21898 | 2.1 |
| Protein-binding VH sdAb | 388 | 182243 | 7890 | 39058 | 8772 | 40695 | 2.1 |
| Peptide-binding VH sdAb | 14 | 5377 | 276 | 1316 | 155 | 936 | 1.9 |
| Protein-binding VL sdAb | 4 | 1304 | 62 | 309 | 52 | 250 | 2.2 |
| Peptide-binding VL sdAb | 2 | 377 | 20 | 92 | 12 | 78 | 2.7 |