Table 2.
F. hepatica NEJs glycoproteins carrying unusual N- or O-glycan structures
| Name (accession) | Extract | Glycan |
|---|---|---|
| Uncharacterized protein (BN1106_s574B000140) | ES | O-PC |
| Cathepsin B2 (FhCB2) (BN1106_s4482B000044) | ES/Som | Multiple PC |
| Cathepsin B11 (FhCB11) (maker-scaffold10x_889_pilon-snap-gene-0.33) | ES/Som | Multiple PC |
| Legumain 2 (BN1106_s2087B000065) | ES/Som | Multiple PC |
| CUB domain-containing protein (BN1106_s7704B000009) | ES/Som | Multiple PC |
| Uncharacterized protein - CUB (BN1106_s5172B000090) | ES/Som | Multiple PC |
| Acid sphingomyelinase phosphodiesterase 3a (BN1106_s1285B000159) | ES/Som | Multiple PC |
| Uncharacterized protein (A0A4E0R0K3) | ES/Som | PC |
| Uncharacterized protein - CD59-like (BN1106_s5246B000010) | ES/Som | PC |
| Uncharacterized protein - CUB (BN1106_s114B000622) | ES/Som | PC |
| CUB domain-containing protein (maker-scaffold10x_280_pilon-snap-gene-0.116) | ES/Som | PC |
| Laminin subunit beta (BN1106_s1357B000110) | ES/Som | PC |
| Low-density lipoprotein receptor (Ldl) (BN1106_s60B000536) | ES/Som | PC |
| Basement membrane-specific heparan sulfate proteoglycan core protein (BN1106_s25B000189) | ES/Som | PC |
| SCP domain-containing protein/Peptidase inhibitor 16 (BN1106_s10890B000012) | ES/Som | O-GalNAc-Pent |
| Tenascin (BN1106_s115B000510) | Som | O-PC |
| Uncharacterized protein (A0A4E0RHQ9) | Som | O-GalNAc-Pent |
| Uncharacterized protein (BN1106_s1308B000129) | Som | O-GalNAc-Pent |
| Uncharacterized protein (maker-scaffold10x_2189_pilon-snap-gene-0.8) | Som | O-GalNAc-Pent |
| CUB domain-containing protein (A0A4E0RX49) | Som | O-GalNAc-Pent |
| Cathepsin L4 (FhCL4_1) (BN1106_s6995B000048) | Som | Multiple PC |
| Hemicentin-1 (BN1106_s9952B000009) | Som | Multiple PC |
| Peptidase M60 domain-containing protein (BN1106_s2007B000402) | Som | Multiple PC |
| Uncharacterized protein (BN1106_s3656B000030) | Som | Multiple PC |
| Putative sodium/potassium-transporting ATPase subunit beta-3 (BN1106_s3547B000116) | Som | PC |
ES, Excretory-secretory extract; O-GalNAc-Pent, canonical O-glycan core (GalNAc) modified by a pentose; O-PC, PC motif associated to an O-glycan; PC, Phosphorylcholine; Som, Somatic extract.
Complete glycan structures associated to each glycoprotein can be verified in the Supplementary material 6.