Table 3.
Representative examples of dual-model imaging-guided therapy based on melanin/melanin-like nanoparticles.
| Melanin/melanin-like nanoparticles | Imaging-guided therapy | Cell line in vitro | Disease type | Ref. |
|---|---|---|---|---|
| MNP-Mn | MRI/PAI guided PTT | Hep-2, NIH 3T3 | Tumor | [149] |
| Lip-Mel | MRI/PAI guided PTT | MDA-MB-231 | Tumor | [150] |
| PPBR | MRI/PAI guided autophagy promotion-associated PTT | NIH3T3, Hela, MDA-MB-231 | Tumor | [151] |
| OBX-MMNs | MRI/PAI guided mild hyperthermia-enhanced chemotherapy | MDA-MB-231, MDA-MB-468 | Tumor | [152] |
| IR820-PEG-MNPs | PAI/MRI guided selective ablation | HepG2, Huh7 | Tumor | [153] |
| ANG-MnEMNPs-Cur (AMEC) | MRI/PAI guided antioxidation and anti-neuroinflammation | bEnd. 3 | Traumatic Brain injury | [154] |
| SRF-MNPs | PAI/PET-guided chemotherapy | NIH 3T3, HepG2 | Tumor | [28] |
| MNP-PEG-H2 | NIR-II FLI/PAI tracking hUMSCs and liver regeneration therapy | hUMSCs | Acute liver injury | [155] |
| Pt(II) metallacycle/NIR-II molecular dye/melanin dots | NIR-II/PAI guided chemo-PTT therapy | U87MG | Tumor | [156] |
| Gd-Mel@SiO2 | MRI/FI guided PTT therapy | PC-3 | Tumor | [157] |
| Mn2+-chelated melanin nanoparticles (MMMP) | PET/MRI guided antioxidant therapy | HEK293 | Acute kidney injury | [158] |
| CH-4T/SLB–MSN–Mdot /64Cu2+ |
NIR-II FL/PET guided surgery | NIH3T3, A431 | Tumor | [159] |