Figure 1.

Group classification and experimental overview. A total of 56 mice were included in the study. Among them, 49 mice were induced with dry eye for 10 days. They were then divided into 2 groups: one received cyclosporine (CsA) treatment, and the other received normal saline (NS) for 3, 7, and 14 days. Clinical battery tests and conjunctival goblet cell analysis were conducted after the treatment period. Additionally, seven mice without dry eye induction served as the negative control group, whereas seven mice with induced dry eye served as the positive control group (n = 7).