Table 3.
Spearman correlations between major depressive disorder symptom severity at baseline and at episode recurrence at 2-, 4-, 6- and 9-year follow-upa
IDS symptom | 2 years (n = 302) | 4 years (n = 229) | 6 years (n = 190) | 9 years (n = 154) | |
---|---|---|---|---|---|
Core symptoms | |||||
Depressed mood | Baseline | 0.34 | 0.34 | 0.28 | 0.32 |
2 years | − | 0.43 | 0.29 | 0.31 | |
4 years | − | − | 0.25 | 0.26 | |
6 years | − | − | − | 0.56 | |
Anhedonia | Baseline | 0.39 | 0.39 | 0.36 | 0.26 |
2 years | − | 0.45 | 0.45 | 0.24 | |
4 years | − | − | 0.45 | 0.44 | |
6 years | − | − | − | 0.58 | |
Non-core symptoms | |||||
Fatigue/loss of energy | Baseline | 0.39 | 0.32 | 0.28 | 0.21 |
2 years | − | 0.45 | 0.41 | 0.26 | |
4 years | − | − | 0.51 | 0.32 | |
6 years | − | − | − | 0.40 | |
Appetite/weight change | |||||
Appetite increase | Baseline | 0.55 | 0.47 | 0.31 | 0.49 |
2 years | − | 0.60 | 0.43 | 0.44 | |
4 years | − | − | 0.46 | 0.46 | |
6 years | − | − | − | 0.42 | |
Appetite decrease | Baseline | 0.42 | 0.28 | 0.28 | 0.32 |
2 years | − | 0.42 | 0.23 | 0.16 | |
4 years | − | − | 0.17 | 0.07 | |
6 years | − | − | − | 0.45 | |
Weight increase | Baseline | 0.25 | 0.23 | .27 | 0.30 |
2 years | − | 0.34 | 0.35 | 0.33 | |
4 years | − | − | 0.44 | 0.26 | |
6 years | − | − | − | 0.42 | |
Weight decrease | Baseline | 0.24 | 0.09 | 0.20 | 0.13 |
2 years | − | 0.03 | 0.36 | 0.07 | |
4 years | − | − | 0.28 | 0.33 | |
6 years | − | − | − | 0.15 | |
Sleep disturbance | |||||
Insomnia | Baseline | 0.56 | 0.59 | 0.59 | 0.60 |
2 years | − | 0.66 | 0.69 | 0.55 | |
4 years | − | − | 0.64 | 0.56 | |
6 years | − | − | − | 0.65 | |
Hypersomnia | Baseline | 0.48 | 0.53 | 0.50 | 0.35 |
2 years | − | 0.51 | 0.55 | 0.35 | |
4 years | − | − | 0.60 | 0.47 | |
6 years | − | − | − | 0.57 | |
Psychomotor disturbance | |||||
Psychomotor agitation | Baseline | 0.48 | 0.21 | 0.43 | 0.26 |
2 years | − | 0.37 | 0.56 | 0.28 | |
4 years | − | − | 0.46 | 0.31 | |
6 years | − | − | − | 0.31 | |
Psychomotor retardation | Baseline | 0.41 | 0.42 | 0.29 | 0.37 |
2 years | − | 0.41 | 0.51 | 0.46 | |
4 years | − | . | 0.59 | 0.42 | |
6 years | − | − | − | 0.45 | |
Worthlessness/guilt | Baseline | 0.40 | 0.37 | 0.34 | 0.31 |
2 years | − | 0.40 | 0.42 | 0.38 | |
4 years | − | − | 0.47 | 0.47 | |
6 years | − | − | − | 0.45 | |
Concentration difficulties | Baseline | 0.40 | 0.26 | 0.24 | 0.28 |
2 years | − | 0.29 | 0.24 | 0.10 | |
4 years | − | − | 0.52 | 0.17 | |
6 years | − | − | − | 0.45 | |
Suicidal ideation | Baseline | 0.46 | 0.48 | 0.36 | 0.48 |
2 years | − | 0.49 | 0.53 | 0.39 | |
4 years | − | − | 0.39 | 0.45 | |
6 years | − | − | − | 0.55 |
IDS, Inventory of Depressive Symptomatology
Interpretation of correlation coefficients based on r = 0.50 indicating large, r = 0.30 medium, and r = 0.10 small correlations.23 Significant correlations based on P < 0.005 are indicated in bold.