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. 2023 Oct 27;9(12):2205–2215. doi: 10.1021/acscentsci.3c01102

Figure 5.

Figure 5

(A) Bacterial growth in lung tissue given as log 10 cfu/g tissue. Mice in all groups were treated with P. aeruginosa DSM-1117. Inoculum control, the number of colony-forming units (cfu) in the lungs was determined 15 min after infection; all other lungs were taken after 24 h; vehicle control: mice treated with a vehicle; LVX 25 mg/kg: mice treated with levofloxacin; 4b 10 mg/kg TID (3 times per day) + LVX 25 mg/kg: mice treated with a combination of 4b and levofloxacin; 4b 10 mg/kg TID: mice treated with 4b. (B) LasB levels in blood in mice infected with P. aeruginosa DSM-1117.