Table 2.

Whole study cohort as well as subgroup volumetric and growth rate results.

Group		Volumes (cc)			Absolute Growth Rate (AGR; cc/yr)
		Baseline	Last on Tx	Best Response	Before treatment	First year	Entire duration
Whole Group (n=12)	Mean	29.5	25.3	23.8	8.0	−0.2	−1.2
	±SD	32.1	22.0	22.5	7.7	7.9	10.6
	p-value	—	ns	0.09	—	0.05	0.05
Grade 2 (N=8)	Mean	36.4	28.5	27.6	7.9	−1.9	−5.6
	±SD	37.2	24.8	25.6	8.4	8.3	7.4
	p-value	—	ns	0.07	—	0.09	0.04
Grade 3 (N=4)	Mean	15.8	18.8	16.2	8.0	3.2	7.5
	±SD	13.3	16.1	14.2	7.3	6.9	11.5
	p-value	—	ns	ns	—	ns	ns
Small Tumors (n=6)	Mean	7.4	10.2	8.0	2.1	3.2	2.1
	±SD	5.1	6.5	5.1	1.6	4.9	5.0
	p-value	—	ns	ns	—	ns	ns
Large Tumors (n=6)	Mean	51.7	40.4	39.7	13.8	−3.7	−4.5
	±SD	32.7	21.9	21.9	6.9	9.3	14.1
	p-value	—	ns	0.07	—	0.01	0.03

Large tumor defined as ≥14 cc at baseline based on the studied populations median.