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. 2023 Sep 12;25(1):15–23. doi: 10.1097/PCC.0000000000003371

TABLE 2.

Safety of Epoprostenol: Number of Filters Used and Associated Complications Expressed as Number of Events and Percentage and Rate per 1,000 Hours of Continuous Renal Replacement Therapy

Outcome All Patients (18,508 hr, 353 Filters) ALF (9,366.5 hr, 176 Filters) Other Liver Diagnoses (9,141.5 hr, 177 Filters) ALF vs Other Liver Diagnoses
n (% of Filters) Rate Per 1,000 hr n (%) Rate Per 1,000 hr n (% of Filters) Rate Per 1,000 hr p
Number of episodes of major bleeding 21 (5.9%) 1.13 10 (5.7%) 1.07 11 (6.2%) 1.20 0.832
Number of episodes of minor bleeding 18 (5.1%) 0.97 11 (6.3%) 1.17 7 (4.0%) 0.77 0.327
Number of episodes of hypotension 41 (11.6%) 2.22 21 (11.9%) 2.24 20 (11.3%) 2.19 0.853
Number of platelet transfusions (at 10 mL/kg) 149.8 8.09 70.7 7.55 79.1 8.65 0.450
Number of RBC transfusions (at 15 mL/kg) 90.9 4.91 49.9 5.33 41.1 4.50 0.357

ALF = acute lung failure.