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. 2005 Mar;79(6):3703–3712. doi: 10.1128/JVI.79.6.3703-3712.2005

FIG. 2.

FIG. 2.

Expression of early and late proteins in lytically induced 293-BFRF1-KO cell lines. The results of an immunofluorescence assay performed on lytically induced 293-2089, 293-BFRF1-KO, and BFRF1-complemented 293-BFRF1-KO cell lines are shown. Lytically induced 293-BFRF1-KO cells do not show any expression of BFRF1 (b) compared to the wild-type 293-2089 cells or to the BFRF1-complemented 293BFRF1-KO cells (a and c, respectively), while the expression of the immediate-early antigen Rta (e), as well as of the late antigens BLLF1 (h) and BLRF2 (k), is still maintained in the 293-BFRF1-KO cell line at a level comparable to that in the wild-type or the BFRF1 complemented 293-BFRF1-KO cells.