Table 2.
Diagnostic evaluation profiles of ECMO patients with death by neurologic criteria
| ID | Age | Sex | ECMO Mode | Neuro Exam | Head CT | Apnea Test | EEG | TCD |
|---|---|---|---|---|---|---|---|---|
| 1 | 51 | M | VA | No reflexes | Severe cerebral edema with uncal herniation | + | Absent reactivity, low voltage, and absent physiologic patterns | Absent waveforms and pulsatile indices |
| 2 | 41 | F | VA | No reflexes | Diffuse ischemic injury and uncal herniation | Not Performed | Absent cerebral activity | Short systolic spikes |
| 3 | 42 | F | VA | No reflexes | Intraparenchymal hemorrhage | + | Not Performed | Posterior cerebral circulatory arrest |
| 4 | 43 | M | VV | No reflexes | Intraparenchymal and subarachnoid hemorrhages with midline shift | + | Suppressed cerebral activity with absent variability and reactivity | Not Performed |
| 5 | 57 | M | VV | No reflexes | Diffuse cerebral edema, cerebellar hemorrhage with tonsillar herniation | + | Extremely low voltage with no reactivity or spontaneous variability | Short systolic spikes |
| 6 | 48 | M | VV | No reflexes | Intraparenchymal hemorrhage with uncal herniation | + | Not Performed | Not Performed |
| 7 | 42 | M | VA | No reflexes | Diffuse cerebral edema with brainstem compression | Not Performed | Absent cerebral activity | Not Performed |
| 8 | 45* | M | VV | No reflexes | Intraparenchymal hemorrhage | + | Not Performed | Anterior and posterior cerebral circulatory arrest with short systolic spikes |
Consistent with death by neurologic criteria. -: Not consistent with death by neurologic criteria
Had single photon emission computed tomography with Technetium-99m hexamethyl propylenamine oxime (HMPAO-SPECT) consistent with brain death