TABLE 4.
Postoperative adjuvant therapy alone or in combination with immunotherapy‐related adverse reactions after propensity score matching.
| Adverse event | AC + IM groups (n = 32) | AC groups (n = 32) | ||
|---|---|---|---|---|
| Grade 1 and 2 (%) | Grade 3 and 4 (%) | Grade 1 and 2 (%) | Grade 3 and 4 (%) | |
| Nausea | 20 (63) | 0 | 19 (59) | 0 |
| Diarrhea | 16 (50) | 0 | 17 (53) | 0 |
| Rash | 16 (50) | 1 (3) | 13 (41) | 2 (6) |
| Hand–foot syndrome | 12 (38) | 0 | 14 (44) | 0 |
| Fatigue | 11 (34) | 0 | 15 (47) | 0 |
| Leucopenia | 11 (34) | 2 (6) | 12 (38) | 2 (6) |
| Anemia | 10 (31) | 2 (6) | 7 (22) | 1 (3) |
| Thrombocytopenia | 8 (25) | 1 (3) | 7 (22) | 0 |
| ALT elevation | 5 (16) | 0 | 7 (22) | 0 |
| AST elevation | 4 (13) | 0 | 6 (19) | 0 |
| TBIL elevation | 4 (13) | 0 | 5 (16) | 0 |
| Proteinuria | 4 (13) | 2 (6) | 3 (9) | 3 (9) |
| Hematuresis | 3 (9) | 2 (6) | 3 (9) | 2 (6) |
| Creatinine elevation | 3 (9) | 0 | 3 (9) | 0 |