FIG. 5.

MyD88-dependent and -independent signaling linked to RSV-induced chemokine production. A549 cells were transfected with random siRNA or siRNA toward TLR3 and MyD88. Twelve hours after transfection, cells were infected with RSV at an MOI of 1. At 48 hpi, RNA and protein expression levels of chemokines were determined. Data are representative of three experiments, with n = 3 per treatment per experiment. Each time point represents the mean ± standard error of the mean. The asterisk indicates statistically significant (P < 0.05) decreases compared to RSV-infected cells transfected with random siRNA.