Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Dec 15;14:1267996. doi: 10.3389/fendo.2023.1267996

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Wu, Arya, Huang, McMullen and Nagy

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

RIP3 kinase activity was involved in FFC-induced metabolic disturbances and regulation of genes involved in lipogenesis. Rip3^+/+ and Rip3^K51A/K51A mice were allowed free access to chow or FFC diet for 12 weeks. (A) Plasma concentrations of blood glucose, insulin and calculated HOMA-IR, as well as (B) cholesterol and triglycerides in plasma from Rip3^+/+ and Rip3^K51A/K51A mice. (C) Expression of lipogenesis-related mRNA including Srebp-1c, Pparγ, Fabp4, Fas and Mgat, in the liver was determined by qRT-PCR. Expression was normalized to 18S rRNA and expressed as the percent increase over chow-fed controls. Values represent means ± SEM. Values with different superscripts are significantly different from each other, n = 5-6 per group. p <0.05, assessed by ANOVA.