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. 2023 Oct 17;12(20):e029552. doi: 10.1161/JAHA.123.029552

Figure 2. Total triglycerides and triglycerides in low‐density lipoprotein (LDL) vs coronary heart disease risk, adjusted for lipoprotein particle concentration.

Figure 2

Hazard ratios (HRs) per usual SD higher level of triglycerides among 89 422 participants (stratified by quintiles). A, Total triglycerides. Total triglyceride is triglyceride concentration in all lipoprotein particles. B, Triglycerides in LDL. Triglyceride in LDL is average triglyceride molecules per LDL particle. HRs calculated by Cox proportional hazards models stratified by age and sex and adjusted for ethnicity, education, region, Townsend Deprivation Index, smoking, alcohol, body mass index, and concentration of very‐low‐density lipoprotein, LDL, and high‐density lipoprotein particles. “Usual” levels are estimated from the mean value at resurvey within each baseline‐defined group, providing an unbiased estimate of the long‐term average level in each baseline‐defined group. “Usual SD” was obtained from the baseline SD through multiplication by square root of the regression dilution ratio. Area of the square is inversely proportional to the variance of the category‐specific log risk. CI indicates confidence interval; HDL, high‐density lipoproteins; HR, hazard ratio; LDL, low‐density lipoproteins; SD, standard deviation; and VLDL, very‐low‐density lipoproteins.