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. 2023 Oct 28;119(17):2755–2769. doi: 10.1093/cvr/cvad164

Figure 2.

Figure 2

Adipocyte-specific NOS3 KO potentiates HFD-induced hypertension despite less weight gain. (A) Body weight of control and A-NOS3 KO mice measured at 8 weeks old (before the experiment). (B) Body weight of control and A-NOS3 KO mice fed with either NCD or HFD measured at the age of 28 weeks (after 20 weeks of NCD/HFD feeding). (C) Systolic, diastolic and mean arterial blood pressure of mice at the age of 28 weeks was measured by the non-invasive tail-cuff method. One-way ANOVA followed by Tukey's post hoc test was used to compare multiple groups. *P < 0.05 vs. control of the same diet. #P < 0.05 vs. NCD of the same genotype.