TABLE 2.
Baseline characteristics and laboratory results in patients with good and poor outcomes at 3 months after PSM.
| Variable | All patients (n = 204) | Good outcome (n = 102) | Poor outcome (n = 102) | p Value |
|---|---|---|---|---|
| Characteristics | ||||
| Age (median [IQR]) | 75.00 [65.00, 83.00] | 74.00 [65.25, 82.00] | 76.00 [63.25, 83.75] | .848 |
| Gender (male), N (%) | 111 (54.4) | 55 (53.9) | 56 (54.9) | 1.000 |
| Stroke severity, N (%) | .980 | |||
| NIHSS score (0–4) | 38 (18.6) | 19 (18.6) | 19 (18.6) | |
| NIHSS score (5–15) | 132 (64.7) | 67 (65.7) | 65 (63.7) | |
| NHISS score (16–20) | 26 (12.7) | 12 (11.8) | 14 (13.7) | |
| NIHSS score (21–42) | 8 (3.9) | 4 (3.9) | 4 (3.9) | |
| Subgroup of TOAST, N (%) | 1.000 | |||
| Small‐artery occlusion | 43 (21.1) | 21 (20.6) | 22 (21.6) | |
| Large‐artery atherosclerosis | 71 (34.8) | 36 (35.3) | 35 (34.3) | |
| Cardio‐embolism | 76 (37.3) | 38 (37.3) | 38 (37.3) | |
| Undetermined etiology | 10 (4.9) | 5 (4.9) | 5 (4.9) | |
| Other etiology | 4 (2.0) | 2 (2.0) | 2 (2.0) | |
| Infarct location, n (%) | .867 | |||
| Anterior circulation | 158 (77.5) | 78 (76.5) | 80 (78.4) | |
| Posterior circulation | 46 (22.5) | 24 (23.5) | 22 (21.6) | |
| DNT, min (median [IQR]) | 45.00 [34.00, 65.50] | 44.00 [35.00, 61.75] | 45.00 [33.00, 67.00] | .834 |
| OTT, min (median [IQR]) | 128.00 [89.00, 165.00] | 125.50 [85.25, 166.25] | 128.00 [91.25, 165.00] | .976 |
| Hypertension, N (%) | 149 (73.0) | 72 (70.6) | 77 (75.5) | .528 |
| Diabetes, N (%) | 62 (30.4) | 26 (25.5) | 36 (35.3) | .171 |
| Smoking, N (%) | 67 (32.8) | 31 (30.4) | 36 (35.3) | .551 |
| Drinking, N (%) | 37 (18.1) | 18 (17.6) | 19 (18.6) | 1.000 |
| AF, N (%) | 73 (35.8) | 36 (35.3) | 37 (36.3) | 1.000 |
| Prior stroke or TIA, N (%) | 40 (19.6) | 18 (17.6) | 22 (21.6) | .597 |
| Laboratory results | ||||
| Hs‐CRP, mg/L (median [IQR]) | 3.00 [1.60, 6.00] | 2.45 [1.60, 5.00] | 3.00 [1.60, 7.00] | .220 |
| FBG, mmol/L (median [IQR]) | 7.20 [6.10, 9.93] | 7.00 [6.10, 9.57] | 7.35 [6.10, 10.35] | .652 |
| Hba1c (%) (median [IQR]) | 6.05 [5.60, 6.95] | 6.10 [5.70, 7.02] | 5.95 [5.60, 6.90] | .506 |
| FIB, g/L (median [IQR]) | 2.66 [2.25, 3.18] | 2.58 [2.16, 2.95] | 2.78 [2.32, 3.34] | .009* |
| ALB, g/L (median [IQR]) | 40.00 [37.85, 43.00] | 40.00 [38.00, 42.30] | 40.00 [37.00, 43.08] | .903 |
| FAR (median [IQR]) | 6.56 [5.63, 7.93] | 6.27 [5.56, 7.42] | 7.04 [5.76, 8.40] | .016* |
*p < .05.
Abbreviations: AF, atrial fibrillation; ALB, albumin; DNT, door‐to‐needle time; FAR, fibrinogen‐to‐albumin ratio; FBG, fasting blood glucose; FIB, fibrinogen; Hba1c, glycosylated hemoglobin; Hs‐CRP, high‐sensitivity C‐reactive protein; IQR, interquartile range; NIHSS, National Institutes of Health Stroke Scale; OTT, the time from onset to treatment; PSM, propensity score matching; TIA, transient ischemic attack; TOAST, the Trial of Org 10172 in Acute Stroke Treatment.