Skip to main content
. 2024 Jan 1;21(2):376–395. doi: 10.7150/ijms.92131

Table 3.

Particulars of SNPs used in MR analyses of gut microbiota

Exposure traits SNPs EA OA Beta Se samplesize P-value R2 F-statistic
Type 2 diabetes (P<1×10-12) rs2296173 G A 0.065 0.0087 62892 7.65773E-14 0.001 55.820
rs340874 C T 0.0626 0.0073 62892 8.40621E-18 0.001 73.536
rs2972144 G A 0.0913 0.0075 62892 2.55094E-34 0.002 148.190
rs243019 C T 0.0566 0.0071 62892 2.28981E-15 0.001 63.550
rs780094 C T 0.0692 0.0074 62892 5.15941E-21 0.001 87.448
rs17334919 T C -0.1398 0.0128 62892 6.68652E-28 0.002 119.287
rs13389219 T C -0.0722 0.0074 62892 2.1062E-22 0.002 95.194
rs6808574 C T 0.0552 0.0076 62892 4.38531E-13 0.001 52.753
rs11708067 G A -0.0965 0.0086 62892 5.93335E-29 0.002 125.909
rs6795735 T C -0.0558 0.0073 62892 1.63005E-14 0.001 58.428
rs7651090 G A 0.1204 0.0076 62892 3.8539E-57 0.004 250.972
rs1899951 T C -0.1118 0.0109 62892 1.63682E-24 0.002 105.204
rs1496653 G A -0.0769 0.0088 62892 2.57217E-18 0.001 76.364
rs1801214 T C 0.0903 0.0074 62892 5.51569E-34 0.002 148.906
rs459193 G A 0.0711 0.0083 62892 8.80846E-18 0.001 73.381
rs7729395 T C 0.1373 0.016 62892 1.10103E-17 0.001 73.638
rs7756992 G A 0.1297 0.0078 62892 5.99929E-62 0.004 276.497
rs1063355 G T 0.0709 0.0079 62892 3.71535E-19 0.001 80.545
rs17168486 T C 0.0742 0.0094 62892 2.17721E-15 0.001 62.309
rs2191348 T G 0.0652 0.0073 62892 3.44429E-19 0.001 79.772
rs13234269 A T -0.0583 0.0078 62892 6.9775E-14 0.001 55.866
rs849135 A G -0.0999 0.0072 62892 1.04112E-43 0.003 192.516
rs3802177 A G -0.1217 0.008 62892 2.32113E-52 0.004 231.420
rs516946 C T 0.0824 0.0085 62892 3.15864E-22 0.001 93.976
rs10974438 C A 0.0591 0.0075 62892 3.01301E-15 0.001 62.094
rs10811661 C T -0.1569 0.0098 62892 4.13238E-58 0.004 256.327
rs2796441 A G -0.0715 0.0073 62892 1.962E-22 0.002 95.933
rs1063192 A G 0.0634 0.0073 62892 3.29837E-18 0.001 75.428
rs4918796 C T 0.0623 0.0086 62892 4.01328E-13 0.001 52.478
rs7923866 T C -0.0972 0.0074 62892 9.33684E-40 0.003 172.532
rs11257655 T C 0.0737 0.0087 62892 1.96607E-17 0.001 71.762
rs7903146 T C 0.3059 0.0077 62892 1E-200 0.024 1578.256
rs10830963 G C 0.0909 0.008 62892 5.84655E-30 0.002 129.106
rs1552224 C A -0.1034 0.0101 62892 8.63575E-25 0.002 104.809
rs5215 T C -0.0678 0.0073 62892 2.08882E-20 0.001 86.261
rs10842994 T C -0.0755 0.0091 62892 1.01508E-16 0.001 68.835
rs2261181 T C 0.0985 0.0118 62892 9.1791E-17 0.001 69.680
rs825476 T C 0.0524 0.0073 62892 6.80456E-13 0.001 51.525
rs61953351 T G -0.07 0.0091 62892 1.97606E-14 0.001 59.172
rs1359790 A G -0.0796 0.008 62892 2.79512E-23 0.002 99.003
rs7177055 A G 0.0647 0.0079 62892 2.746E-16 0.001 67.074
rs7185735 G A 0.1056 0.0073 62892 1.59001E-47 0.003 209.258
rs77258096 A C -0.1171 0.0134 62892 1.7832E-18 0.001 76.367
rs8068804 A G 0.0587 0.0078 62892 4.41062E-14 0.001 56.635
rs9894220 G A -0.0585 0.0079 62892 1.51705E-13 0.001 54.835
rs8108269 G T 0.0644 0.0079 62892 3.11387E-16 0.001 66.453
coronary artery disease (P<1×10-10) rs67180937 G T 0.078807 0.0110551 42457 1.01E-12 0.001 50.816
rs7528419 G A -0.11453 0.011482 42457 1.97E-23 0.002 99.495
rs9970807 T C -0.12575 0.016695 42457 5.00E-14 0.001 56.734
rs115654617 A C 0.137846 0.0158314 42457 3.12E-18 0.002 75.814
rs12202017 G A -0.066813 0.0099612 42457 1.98E-11 0.001 44.988
rs55730499 T C 0.316641 0.0242403 42457 5.39E-39 0.004 170.631
rs186696265 T C 0.550351 0.0481949 42457 3.35E-30 0.003 130.400
rs9349379 G A 0.131836 0.0096527 42457 1.81E-42 0.004 186.539
rs2107595 A G 0.073415 0.0112951 42457 8.05E-11 0.001 42.246
rs11556924 T C -0.072569 0.0110605 42457 5.34E-11 0.001 43.048
rs2891168 G A 0.193401 0.0091877 42457 2.29E-98 0.010 443.102
rs2487928 A G 0.062633 0.0095049 42457 4.41E-11 0.001 43.422
rs1870634 G T 0.075878 0.0097113 42457 5.55E-15 0.001 61.049
rs1412444 T C 0.066812 0.0096809 42457 5.15E-12 0.001 47.630
rs2128739 C A -0.065565 0.0100568 42457 7.05E-11 0.001 42.503
rs2681472 G A 0.074114 0.0113331 42457 6.17E-11 0.001 42.766
rs4468572 C T 0.077234 0.0095277 42457 4.44E-16 0.002 65.711
rs4420638 G A 0.091906 0.0140977 42457 7.07E-11 0.001 42.500
rs56289821 A G -0.13361 0.0170415 42457 4.44E-15 0.001 61.470
rs28451064 A G 0.127571 0.015952 42457 1.33E-15 0.002 63.955
genus Lachnoclostridium id.11308 (P<1×10-5) rs12566975 T C -0.0468097 0.0105787 14306 9.57194E-06 0.001 19.580
rs1528479 A G 0.0497799 0.0111919 14306 9.63984E-06 0.001 19.783
rs615997 T C 0.0511752 0.0106491 14306 2.0268E-06 0.002 23.094
rs62285313 A G 0.0864203 0.0181565 14306 1.58332E-06 0.002 22.655
rs1031599 T G 0.078627 0.0175644 14306 6.31379E-06 0.001 20.039
rs3821998 C A -0.0864066 0.0192519 14306 6.72048E-06 0.001 20.144
rs4738679 A G 0.0520267 0.011404 14306 4.41754E-06 0.001 20.813
rs1997204 C T 0.108075 0.0242022 14306 5.97077E-06 0.001 19.941
rs62028349 G C 0.0469989 0.0105971 14306 9.17044E-06 0.001 19.670
rs72829893 G T 0.117472 0.0268103 14306 5.57763E-06 0.001 19.198
rs78068103 A G 0.0886199 0.0194248 14306 3.66522E-06 0.001 20.814
rs2385421 A G 0.0746186 0.0180734 14306 7.13724E-06 0.001 17.046
rs789029 C T -0.0641288 0.0137974 14306 3.75327E-06 0.002 21.603
rs6112314 A C -0.0561715 0.0108174 14306 2.43215E-07 0.002 26.964
genus Streptococcus id.1853 (P<1×10-5) rs11720390 G A 0.107024 0.0228121 14306 3.59484E-06 0.002 22.011
rs6806351 T C -0.0633829 0.0136647 14306 4.93867E-06 0.002 21.515
rs57646748 G A -0.0907696 0.0200344 14306 5.47545E-06 0.001 20.527
rs10028567 C T -0.0921167 0.0191881 14306 7.30348E-06 0.002 23.047
rs395407 C G 0.0792781 0.0173697 14306 4.36506E-06 0.001 20.832
rs77558518 A G -0.103999 0.0229714 14306 4.70858E-06 0.001 20.497
rs11764382 A G -0.0695345 0.0143671 14306 1.28632E-06 0.002 23.424
rs17708276 A G -0.0793955 0.0170628 14306 3.04096E-06 0.002 21.652
rs10448310 A G -0.0517935 0.0111324 14306 3.30704E-06 0.002 21.646
rs71481756 T G 0.0931048 0.0207949 14306 6.51478E-06 0.001 20.046
rs7916711 A G 0.102891 0.0217362 14306 0.000002717 0.002 22.407
rs1918540 A G -0.059639 0.0128148 14306 2.44068E-06 0.002 21.659
rs11110281 T C -0.137519 0.0227398 14306 2.58315E-09 0.003 36.572
rs2370083 G T -0.0816836 0.0185851 14306 9.75237E-06 0.001 19.317
rs72739637 A G 0.0959942 0.0193213 14306 1.03307E-06 0.002 24.684
rs6563952 C G -0.0827344 0.0180035 14306 5.8213E-06 0.001 21.118
rs4968759 A G -0.0515109 0.0112068 14306 3.7812E-06 0.001 21.127
rs9903102 C A -0.0709483 0.0155275 14306 4.17994E-06 0.001 20.878
genus Actinomyces id.423 (P<1×10-5) rs71315246 A G -0.0969809 0.021925 14306 9.82969E-06 0.001 19.566
rs34583783 G T 0.126596 0.0268461 14306 4.48528E-06 0.002 22.237
rs4073240 G A 0.0749687 0.0167368 14306 7.94273E-06 0.001 20.064
rs35011108 A G 0.232634 0.0512044 14306 6.33826E-06 0.001 20.641
rs4146653 G A 0.0985224 0.0214182 14306 4.49645E-06 0.001 21.159
rs10787984 G C 0.094316 0.0213513 14306 9.62299E-06 0.001 19.513
rs7915461 C T -0.18776 0.0401636 14306 5.91984E-06 0.002 21.855
rs2715439 T C -0.0746684 0.0164822 14306 6.27004E-06 0.001 20.523
family Streptococcaceae id.1850 (P<1×10-5) rs77968078 G A -0.0993013 0.0224788 14306 7.93341E-06 0.001 19.515
rs76717940 T A 0.150606 0.0334079 14306 3.08937E-06 0.001 20.323
rs6806351 T C -0.0619209 0.0135744 14306 6.93793E-06 0.001 20.808
rs10028567 C T -0.0934027 0.0190343 14306 3.72495E-06 0.002 24.079
rs57646748 G A -0.088021 0.019876 14306 7.88352E-06 0.001 19.612
rs395407 C G 0.0826855 0.0172536 14306 1.32559E-06 0.002 22.967
rs77558518 A G -0.104239 0.022806 14306 3.72195E-06 0.001 20.891
rs957755 T G -0.0642449 0.0142702 14306 7.41515E-06 0.001 20.268
rs2952251 G A 0.0639298 0.0126525 14306 3.72237E-07 0.002 25.530
rs28718126 A G 0.109069 0.0246868 14306 9.41044E-06 0.001 19.520
rs7916711 A G 0.0959639 0.021545 14306 6.32732E-06 0.001 19.839
rs16950051 A G 0.107008 0.0236973 14306 5.33814E-06 0.001 20.391
rs11110281 T C -0.130554 0.0225943 14306 1.40136E-08 0.002 33.387
rs2370083 G T -0.0842751 0.0184509 14306 4.25667E-06 0.001 20.862
rs72739637 A G 0.0927983 0.0192021 14306 1.82163E-06 0.002 23.355
rs6563952 C G -0.0801931 0.0178576 14306 8.70583E-06 0.001 20.166
rs35344081 G A 0.0609349 0.0129703 14306 2.63846E-06 0.002 22.072
rs9903102 C A -0.0693015 0.0154096 14306 4.91802E-06 0.001 20.226
rs4968759 A G -0.0544035 0.0111271 14306 8.91887E-07 0.002 23.905
unknown genus id.2041 (P<1×10-5) rs1032598 G A -0.0886426 0.0189039 14306 4.07587E-06 0.002 21.988
rs16843660 A G 0.234697 0.04907 14306 1.75344E-06 0.002 22.876
rs11941716 A G 0.101243 0.0224414 14306 9.0663E-06 0.001 20.353
rs249459 A G 0.0737341 0.0165018 14306 8.12307E-06 0.001 19.965
rs553072 G A 0.109193 0.0230198 14306 3.69097E-06 0.002 22.500
rs1962916 G A -0.0737876 0.0162232 14306 6.13847E-06 0.001 20.687
rs35703006 G T 0.0926669 0.0190779 14306 9.00762E-07 0.002 23.593
rs921383 G A 0.0723153 0.0159706 14306 7.72894E-06 0.001 20.503
rs2651663 A G -0.0762556 0.0168635 14306 5.64144E-06 0.001 20.448
rs2336448 T C 0.0773742 0.0160883 14306 1.42899E-06 0.002 23.130
rs7187855 A C 0.199941 0.0418308 14306 2.20602E-06 0.002 22.846
rs6514318 T C 0.128198 0.0281765 14306 5.37675E-06 0.001 20.701
genus Oxalobacter id.2978 (P<1×10-5) rs4428215 G A 0.130293 0.0242237 14306 7.51069E-08 0.002 28.931
rs36057338 G T 0.207847 0.0421439 14306 8.79812E-07 0.002 24.323
rs1569853 T C -0.138078 0.0296981 14306 3.64502E-06 0.002 21.617
rs6993398 G A 0.127217 0.0278855 14306 7.12771E-06 0.001 20.813
rs10464997 G A 0.137691 0.0294804 14306 3.29754E-06 0.002 21.814
rs12002250 A C 0.217122 0.0466317 14306 1.41504E-06 0.002 21.679
rs736744 T C -0.117882 0.0211262 14306 2.57472E-08 0.002 31.135
rs3862635 C T -0.172142 0.0394026 14306 9.18692E-06 0.001 19.086
rs11108500 A G -0.199099 0.0427327 14306 3.74283E-06 0.002 21.708
rs111966731 T C 0.213114 0.047162 14306 7.29861E-06 0.001 20.419
rs6071435 T A -0.105512 0.021489 14306 1.07431E-06 0.002 24.109
rs6000536 C T -0.130992 0.0253804 14306 2.06054E-07 0.002 26.637
genus Turicibacter id.2162 (P<1×10-5) rs149744580 A G 0.169883 0.0315478 14306 7.00971E-08 0.002 28.998
rs4869133 G A 0.131186 0.027197 14306 2.5537E-06 0.002 23.267
rs2221441 G C 0.0710364 0.015343 14306 3.45669E-06 0.001 21.436
rs3734633 G A -0.120957 0.02683 14306 5.31912E-06 0.001 20.325
rs55756211 T C -0.115115 0.0240708 14306 2.8053E-06 0.002 22.871
rs2952020 A G 0.0759019 0.0165764 14306 5.63313E-06 0.001 20.966
rs61265175 G C -0.0858591 0.0185778 14306 4.13676E-06 0.001 21.359
rs11054680 T C -0.104751 0.0226997 14306 2.30978E-06 0.001 21.295
rs4247078 G C -0.0710377 0.0155221 14306 5.46072E-06 0.001 20.945
rs11649454 G C 0.0950891 0.0203433 14306 3.26625E-06 0.002 21.848
rs7199484 G A -0.0731428 0.0160172 14306 5.7666E-06 0.001 20.853
rs12603364 T C 0.110861 0.0225598 14306 8.66603E-07 0.002 24.148
rs11666533 C T -0.111689 0.0248436 14306 7.37106E-06 0.001 20.211
rs2834977 T C -0.0959995 0.0208261 14306 3.95585E-06 0.001 21.248
genus Butyricicoccus id.2055 (P<1×10-5) rs12034718 G A -0.0701199 0.0158213 14306 9.57679E-06 0.001 19.643
rs10084203 G A -0.0549699 0.0123563 14306 8.58638E-06 0.001 19.791
rs56221232 T C 0.0828027 0.0167401 14306 7.61939E-07 0.002 24.467
rs2017189 T G 0.0506956 0.011024 14306 3.87258E-06 0.001 21.148
rs62478070 T G 0.224039 0.0494959 14306 5.93772E-06 0.001 20.488
rs4962426 T G -0.0614216 0.0135979 14306 7.38482E-06 0.001 20.403
rs7322368 C T -0.0815733 0.0183167 14306 5.51785E-06 0.001 19.834
rs12585793 T C -0.262206 0.0564729 14306 5.79189E-06 0.002 21.558
rs75238760 T A 0.0619423 0.0139942 14306 6.79704E-06 0.001 19.592
unknown genus id.2071 (P<1×10-5) rs4644504 T C -0.0969321 0.0216146 14306 5.81969E-06 0.001 20.111
rs11809762 G A -0.0934634 0.0190198 14306 1.68287E-06 0.002 24.147
rs11904514 A G 0.109498 0.0249839 14306 7.89951E-06 0.001 19.208
rs1809136 C G -0.0994594 0.0228638 14306 8.36989E-06 0.001 18.923
rs16823675 C T -0.0767515 0.0149973 14306 2.33346E-07 0.002 26.191
rs11684166 A G -0.0769635 0.0168349 14306 3.49116E-06 0.001 20.900
rs10200320 T C -0.0641139 0.0142769 14306 5.6607E-06 0.001 20.167
rs2898979 G C 0.0901515 0.0202199 14306 7.67291E-06 0.001 19.879
rs35740166 C T -0.112246 0.0226824 14306 8.39982E-07 0.002 24.489
rs17086536 C A -0.100851 0.022432 14306 3.3638E-06 0.001 20.213
rs34985298 G A -0.0623526 0.013772 14306 8.33758E-06 0.001 20.498
rs1455639 A G -0.0760307 0.0169831 14306 7.83899E-06 0.001 20.042
rs11195523 C A -0.0689278 0.0145351 14306 2.40121E-06 0.002 22.488
rs2939766 A G -0.0591611 0.013042 14306 7.01148E-06 0.001 20.577
rs76532867 T C 0.112353 0.0242364 14306 2.55859E-06 0.001 21.490
rs56975773 T A 0.113282 0.0248859 14306 7.65491E-06 0.001 20.721
rs12147596 C T -0.0719818 0.0141609 14306 2.86207E-07 0.002 25.838
rs72700702 T C -0.091726 0.0189005 14306 1.59272E-06 0.002 23.553
rs72707147 C T 0.110109 0.0244644 14306 6.84022E-06 0.001 20.257
rs6007642 C T -0.0791412 0.0177958 14306 9.95543E-06 0.001 19.777
family Clostridiales vadin BB60 group id.11286 rs7538034 T G -0.078598 0.0165982 14306 2.36706E-06 0.002 22.423
(P<1×10-5) rs6588624 A G 0.0662317 0.0138147 14306 1.79287E-06 0.002 22.985
rs13409132 A G -0.165419 0.0352154 14306 4.3723E-06 0.002 22.065
rs2191834 T G -0.0746375 0.0159136 14306 2.50196E-06 0.002 21.998
rs6755871 C G -0.0613825 0.0138976 14306 9.33061E-06 0.001 19.508
rs989682 A G 0.070194 0.0155364 14306 6.84715E-06 0.001 20.413
rs10517600 G T -0.0626993 0.0139364 14306 6.82763E-06 0.001 20.241
rs34088226 A G -0.117807 0.026924 14306 7.66214E-06 0.001 19.145
rs7725895 A G -0.116224 0.0240367 14306 3.94357E-06 0.002 23.380
rs66714985 A C 0.116908 0.0252447 14306 4.85333E-06 0.001 21.446
rs118104867 C T 0.214464 0.0455098 14306 3.43598E-06 0.002 22.207
rs10904722 C T -0.0672314 0.0147123 14306 5.04836E-06 0.001 20.883
rs17121075 G A 0.0769254 0.0172234 14306 7.91425E-06 0.001 19.948
rs55682560 C T -0.131519 0.0261319 14306 4.97038E-07 0.002 25.330
rs28691777 C T 0.137134 0.0266996 14306 6.95697E-07 0.002 26.380
rs7226487 A G -0.0643682 0.0138701 14306 3.58286E-06 0.002 21.537
rs9979874 G C -0.0738925 0.0150911 14306 1.05271E-06 0.002 23.975
unknown genus id.1000000073 (P<1×10-5) rs6588624 A G 0.0662317 0.0138147 14306 1.79287E-06 0.002 22.985
rs7538034 T G -0.078598 0.0165982 14306 2.36706E-06 0.002 22.423
rs2191834 T G -0.0746375 0.0159136 14306 2.50196E-06 0.002 21.998
rs13409132 A G -0.165419 0.0352154 14306 4.3723E-06 0.002 22.065
rs6755871 C G -0.0613825 0.0138976 14306 9.33061E-06 0.001 19.508
rs989682 A G 0.070194 0.0155364 14306 6.84715E-06 0.001 20.413
rs10517600 G T -0.0626993 0.0139364 14306 6.82763E-06 0.001 20.241
rs7725895 A G -0.116224 0.0240367 14306 3.94357E-06 0.002 23.380
rs34088226 A G -0.117807 0.026924 14306 7.66214E-06 0.001 19.145
rs66714985 A C 0.116908 0.0252447 14306 4.85333E-06 0.001 21.446
rs118104867 C T 0.214464 0.0455098 14306 3.43598E-06 0.002 22.207
rs10904722 C T -0.0672314 0.0147123 14306 5.04836E-06 0.001 20.883
rs17121075 G A 0.0769254 0.0172234 14306 7.91425E-06 0.001 19.948
rs55682560 C T -0.131519 0.0261319 14306 4.97038E-07 0.002 25.330
rs28691777 C T 0.137134 0.0266996 14306 6.95697E-07 0.002 26.380
rs7226487 A G -0.0643682 0.0138701 14306 3.58286E-06 0.002 21.537
rs9979874 G C -0.0738925 0.0150911 14306 1.05271E-06 0.002 23.975
genus Clostridium innocuum group id.14397 rs6577484 G A 0.160425 0.0360857 14306 8.40601E-06 0.001 19.764
(P<1×10-5) rs1948423 T A -0.108859 0.023425 14306 3.49406E-06 0.002 21.596
rs40656 C T 0.142664 0.0311021 14306 8.61529E-06 0.001 21.040
rs6890185 C T -0.113424 0.0233137 14306 1.12243E-06 0.002 23.669
rs4869133 G A -0.180591 0.0409505 14306 7.24453E-06 0.001 19.448
rs10074000 T C -0.102648 0.0227508 14306 6.99939E-06 0.001 20.357
rs71564433 T A -0.126746 0.0274657 14306 7.8001E-06 0.001 21.295
rs10506058 A G 0.0997048 0.0221926 14306 8.92442E-06 0.001 20.184
rs77845139 A G -0.114993 0.0257186 14306 8.40621E-06 0.001 19.992
rs61267978 T C 0.14708 0.0320875 14306 5.58509E-06 0.001 21.010
rs1942371 G A -0.157938 0.034187 14306 4.0634E-06 0.001 21.343
class Lentisphaeria id.2250 (P<1×10-5) rs72640280 A G 0.220207 0.0486196 14306 5.18036E-06 0.001 20.513
rs73113483 T A -0.131217 0.0288713 14306 8.66343E-06 0.001 20.656
rs2731834 G C -0.109438 0.023693 14306 4.24356E-06 0.001 21.335
rs11770843 C T 0.109431 0.0234879 14306 1.9073E-06 0.002 21.707
rs62570196 C T -0.21635 0.0439866 14306 1.07924E-06 0.002 24.192
rs2031282 A G 0.122368 0.0270329 14306 4.38258E-06 0.001 20.490
rs17114848 G A 0.152377 0.0324332 14306 4.05864E-06 0.002 22.073
rs1002941 A G -0.105025 0.0233484 14306 8.14836E-06 0.001 20.234
rs77599476 A G 0.230292 0.0480168 14306 1.86132E-06 0.002 23.002
rs2825714 A G -0.13741 0.0289246 14306 1.72211E-06 0.002 22.568
order Victivallales id.2254 (P<1×10-5) rs72640280 A G 0.220207 0.0486196 14306 5.18036E-06 0.001 20.513
rs73113483 T A -0.131217 0.0288713 14306 8.66343E-06 0.001 20.656
rs2731834 G C -0.109438 0.023693 14306 4.24356E-06 0.001 21.335
rs11770843 C T 0.109431 0.0234879 14306 1.9073E-06 0.002 21.707
rs62570196 C T -0.21635 0.0439866 14306 1.07924E-06 0.002 24.192
rs2031282 A G 0.122368 0.0270329 14306 4.38258E-06 0.001 20.490
rs1002941 A G -0.105025 0.0233484 14306 8.14836E-06 0.001 20.234
rs17114848 G A 0.152377 0.0324332 14306 4.05864E-06 0.002 22.073
rs77599476 A G 0.230292 0.0480168 14306 1.86132E-06 0.002 23.002
rs2825714 A G -0.13741 0.0289246 14306 1.72211E-06 0.002 22.568
genus Bifidobacterium id.436 (P<1×10-5) rs12022129 A G -0.0619356 0.0138937 14306 7.9965E-06 0.001 19.872
rs1961273 C T 0.0674036 0.0132319 14306 3.50865E-07 0.002 25.949
rs13020688 G A 0.0562696 0.0122617 14306 4.07258E-06 0.001 21.059
rs182549 T C -0.119703 0.0127294 14306 1.2782E-20 0.006 88.429
rs62181700 G A -0.0624643 0.0131205 14306 2.17245E-06 0.002 22.665
rs4567981 T A 0.0562084 0.0117923 14306 1.92832E-06 0.002 22.720
rs55888705 A G 0.0546319 0.0121139 14306 6.67022E-06 0.001 20.339
rs4957061 T C 0.0534239 0.0117431 14306 5.77936E-06 0.001 20.697
rs73797465 T G -0.0953566 0.0209236 14306 4.38157E-06 0.001 20.770
rs76671854 C G -0.0846055 0.0184003 14306 3.95667E-06 0.001 21.142
rs857444 C T 0.0558234 0.0121219 14306 0.000003571 0.001 21.208
rs2686790 C T -0.070741 0.0157926 14306 7.49894E-06 0.001 20.065
rs2491158 A G -0.0712624 0.015983 14306 8.04711E-06 0.001 19.879
rs10841473 G C -0.0624207 0.0129438 14306 1.6452E-06 0.002 23.256
rs7322849 T C 0.112428 0.0201813 14306 1.08368E-08 0.002 31.035
rs540489 T G -0.0637641 0.0138746 14306 5.19457E-06 0.001 21.121
rs75344046 C T 0.232354 0.0505979 14306 4.86351E-06 0.001 21.088
rs5746486 T C -0.0536216 0.0120801 14306 8.99953E-06 0.001 19.703

SNPs, single nucleotide polymorphisms; EA, effect allele; OA, other allele; Beta, effect estimate; SE, standard error