Table 3.
Baseline Characteristics of the Study Cohort Classified by SNPs and Genotype
| Variables | AGT rs699 | AGTR1 rs5186 | ||
|---|---|---|---|---|
| CC (N=253) | CT/TT (N=101) | AA (N=301) | AC/CC (N=53) | |
| Age | 52.75 ± 1.37 | 52.57 ± 1.47 | 52.75 ± 1.41 | 52.45 ± 1.36 |
| BMI (kg/m2) | 24.07 ± 2.14 | 25.60 ± 3.09* | 25.46 ± 3.94 | 24.88 ± 3.94 |
| FBG (mg/dL) | 101.73 ± 23.72 | 100.59 ± 16.97 | 101.87 ± 23.16 | 98.79 ± 13.39 |
| HbA1C (%) | 5.97 ± 0.92 | 5.82 ± 0.64 | 5.76 ± 0.66 | 5.96 ± 0.88* |
| TG (mg/dL) | 153.08 ± 109.73 | 144.02 ± 70.80 | 143.11 ± 94.56 | 162.40 ± 86.30* |
| TC (mg/dL) | 200.72 ± 42.91 | 195.01 ± 41.12 | 199.50 ± 43.39 | 196.72 ± 36.75 |
| LDL-C (mg/dL) | 132.69 ± 40.46 | 129.08 ± 38.11 | 132.19 ± 40.59 | 128.64 ± 35.00 |
| HDL-C (mg/dL) | 52.85 ± 13.99 | 52.66 ± 11.33 | 53.05 ± 13.28 | 51.34 ± 13.26 |
| BUN (mg/dL) | 13.52 ± 3.27 | 13.64 ± 3.06 | 13.60 ± 3.20 | 13.29 ± 3.27 |
| Cr (mg/dL) | 1.01 ± 0.15 | 1.01 ± 0.17 | 1.00 ± 0.15 | 1.03 ± 0.15 |
Notes: *Significantly different from CC and AA genotype, p<0.05.
Abbreviations: AGT, angiotensinogen; AGTR1, angiotensin II receptor type 1; BMI, body mass index; BUN, blood urea nitrogen; Cr, creatinine; FBG, fasting blood glucose, HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SNP, single nucleotide polymorphism; TC, total cholesterol; TG, triglycerides.