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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Hepatology. 2023 Apr 17;77(5):1580–1592. doi: 10.1002/hep.32744

FIGURE 2.

FIGURE 2

ST2-deletion delays liver regeneration after PHx. WT and suppression of tumorigenicity 2 (ST2)−/− mice were subjected to PHx. (A, B) Ki67 immunostaining was performed in liver sections collected at 36 h after PHx (scale bar: 100 μm). Ki67-positive hepatocytes were quantified (n = 8–13/group). (C,D) PCNA levels in liver tissues at 36 h after PHx were measured by immunoblotting and the ratios of PCNA/β-actin were quantified (n = 3/group). (E,F) BrdU incorporation was performed in liver sections at 36 h after PHx (scale bar: 100 μm). BrdU positive hepatocytes were quantified (n = 3-4/group). (G) The ratios of liver/body weight were analyzed at 36 h and 168 h after PHx (n = 4–13/group). Two-tailed unpaired Student’s t test was performed in (B), (D), and (F). Two-way ANOVA was performed in (G)