Table 3.
Glucocorticoid dosing in plasma exchange and glucocorticoids in severe ANCA-associated vasculitis study
| Week | Standard-Dose Arm | Reduced-Dose Arm | ||||
|---|---|---|---|---|---|---|
| <50 kg | 50–75 kg | >75 kg | <50 kg | 50–75 kg | >75 kg | |
| Pulse | Pulse | Pulse | Pulse | Pulse | Pulse | |
| 1 | 50 | 60 | 75 | 50 | 60 | 75 |
| 2 | 50 | 60 | 75 | 25 | 30 | 40 |
| 3–4 | 40 | 50 | 60 | 20 | 25 | 30 |
| 5–6 | 30 | 40 | 50 | 15 | 20 | 25 |
| 7–8 | 25 | 30 | 40 | 12.5 | 15 | 20 |
| 9–10 | 20 | 25 | 30 | 10 | 12.5 | 15 |
| 11–12 | 15 | 20 | 25 | 7.5 | 10 | 12.5 |
| 13–14 | 12.5 | 15 | 20 | 6 | 7.5 | 10 |
| 15–16 | 10 | 10 | 15 | 5 | 5 | 7.5 |
| 17–18 | 10 | 10 | 15 | 5 | 5 | 7.5 |
| 19–20 | 7.5 | 7.5 | 10 | 5 | 5 | 5 |
| 21–22 | 7.5 | 7.5 | 7.5 | 5 | 5 | 5 |
| 23–52 | 5 | 5 | 5 | 5 | 5 | 5 |
| >52 | Investigators' local practice | |||||
Glucocorticoid dosing in mg/d.