Table 3.
Univariate and multivariate logistic regression of clinical and pathological factors in the training dataset.
| Characteristics | Univariate |
Multivariate |
|||
|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | β coefficient | P value | |
| Age | 0.959 (0.932–0.986) | 0.004 | 0.957 (0.927–0.988) | −0.044 | 0.007 |
| Menopause | 0.698 (0.366–1.330) | 0.274 | |||
| Bilateral BC | 1.344 (0.601–3.006) | 0.471 | |||
| Previous BC | 1.473 (0.626–3.466) | 0.375 | |||
| Family History∗ | 5.207 (2.910–9.318) | <0.001 | 4.941 (2.670–9.143) | 1.598 | <0.001 |
| ER positive | 0.730 (0.427–1.250) | 0.252 | |||
| PR positive | 0.792 (0.467–1.342) | 0.386 | |||
| HER2 positive | 0.335 (0.153–0.731) | 0.006 | 0.280 (0.122–0.639) | −1.274 | 0.003 |
| Ki-67 ≥ 20% | 5.130 (1.551–16.962) | 0.007 | 4.609 (1.343–15.831) | 1.528 | 0.015 |
| TNBC | 1.738 (0.962–3.139) | 0.067 | |||
BC: breast cancer; ER: oestrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2; TNBC: triple-negative breast cancer.
∗
Family history of BRCA1/2-related malignancy, including breast, ovarian, pancreatic and prostate cancer.