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Multiple sequence alignment. Sequence alignment was obtained by using the CLUSTAL W (version 1.5) program. Residues conserved in all 10 sequences are shaded. Asterisks indicate amino acids involved in metal binding which are conserved between the FeSOD and MnSOD outgroups. Residues that help to distinguish the identity of the metal ligand (Fe or Mn) bound to the SOD apoprotein (35, 36) are boxed at positions 79, 80, 82, and 155.
