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. 2024 Jan 2;14(1):529–537. doi: 10.1039/d3ra07412a

In vitro enzyme inhibition of compounds and antioxidant activity of compounds (1–15).

Compound Urease inhibition IC50 ± SDa Antioxidant activity
% Inhibition ± SDa EC50 (μg ml−1)
1 92.3 ± 0.20 71.1 ± 0.01 37.5
2 73.5 ± 0.65 43 ± 0.01
3 56.3 ± 0.78 67.4 ± 0.01 75
4 34.2 ± 0.72 29 ± 0.01
5 NA 12 ± 0.01
6 NA 71 ± 0.01 37.5
7 NA 57.8 ± 0.01 100
8 86.4 ± 0.78 32 ± 0.01
9 67.14 ± 0.67 57.8 ± 0.02 100
10 NA 57.9 ± 0.02 100
11 42.43 ± 0.65 71.1 ± 0.01 37.5
12 NA 43 ± 0.01
13 NA 57.7 ± 0.01 100
14 NA 23 ± 0.01
15 NA 69.3 ± 0.01 75
Thiourea 21.7 ± 0.12
Acetohydroxamic acid 37.0
Ascorbic acid 80 8.3
a

SD = standard deviation; NA = not applicable.