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. 2023 Dec 18;3:1274599. doi: 10.3389/fbinf.2023.1274599

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Copyright © 2023 Koyama, Hashimoto, Nagao and Mizuguchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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UMAP visualizations of the sequence distance maps of TCRs and peptides in the COVID-19 dataset (upper two figures) and the recent data test set (lower two figures). Each point shows a sequence datum, and the two colors on the peptide side (right two figures) show minimal overlap, indicating different peptides in those data datasets. Left: TCR sequence (CDR3αβ) visualization. Right: peptide sequence visualization. Orange points: the COVID-19 dataset or the recent data test set. Blue points: the combined data dataset.