Table 1.
The area under curve (AUC) values, 95% confidence interval (95%CI), sensitivity, specificity, accuracy, false discovery rate (FDR) adjusted P value and fold change of significantly changed metabolites between gastric cancer patients and healthy controls.
| Name | AUC | 95%CI | Sensitivity (%) | Specificity (%) | Accuracy (%) | FDR adjusted P value | Fold changea |
|---|---|---|---|---|---|---|---|
| Ornithine | 0.75 | 0.53–0.97 | 80 | 79.0 | 79.5 | 0.039 | 1.75 |
| Carnosine | 0.84 | 0.69–0.99 | 80 | 84.2 | 82.1 | 0.0062 | −2.01 |
| Tryptophan | 0.94 | 0.86–1.00 | 90 | 89.5 | 89.8 | 0.00013 | −1.83 |
| 5-aminolevulinic acid | 0.81 | 0.65–0.97 | 80 | 73.7 | 76.9 | 0.0044 | −3.70 |
| Tryptamine | 0.86 | 0.67–1.00 | 80 | 94.7 | 87.4 | 0.0082 | 1.97 |
| Hypotaurine | 0.83 | 0.64–1.00 | 70 | 100.0 | 85.0 | 0.0087 | 1.86 |
| 3-methylhistidine | 0.81 | 0.65–0.97 | 90 | 68.4 | 79.2 | 0.026 | −2.20 |
| Arginine | 0.87 | 0.74–1.00 | 90 | 84.2 | 87.1 | 0.0051 | −1.77 |
a
Fold change was calculated by comparing gastric cancer patient group with healthy controls. Fold change value with a positive value indicates a relatively higher concentration present in gastric cancer group, while a negative value means a relative lower concentration as compared to the control group.