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. 2023 May 12;13(11):1326–1345. doi: 10.1016/j.jpha.2023.05.002

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© 2023 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 6 — Procedure of in vivo experiments and effects of Fe-dihydromyricetin (DMY) nano-coordinated polymer particles (NCPs) treatment on body weight, serum glucose, and food and water intake of rats. High dose: 60 mg/kg and low dose: 10 mg/kg. (A) Schematic diagram of in vitro experimental procedures. (B) Photographs of the ocular surface of rats in different groups. (C−F) Changes in body weight (C), blood glucose (D), water intake (E), and food intake (F) were measured in Sprague-Dawley (SD) rats in different groups during 14 weeks of continuous feeding. Data are expressed as mean ± standard error of mean. Diabetic retinopathy (DR) control (DC) + Fe-DMY (high): DC group treated with high-dose Fe-DMY NCPs (60 mg/kg). DC + Fe-DMY (low): DC group treated with low-dose Fe-DMY NCPs (10 mg/kg). NC: normal control group.