Table 3.
Comparison of bronchiectasis severity index according to the colonization of Haemophilus influenzae
| Variables | Score points | Total |
H. Influenzae
colonizers |
H. Influenzae
non-colonizers |
P |
|---|---|---|---|---|---|
| N = 198 | n = 69 | n = 129 | |||
| Age, years | 0.676 | ||||
| <50 | 0 | 42 (21.2) | 14 (20.3) | 28 (21.7) | |
| 50–69 | 2 | 129 (65.2) | 46 (66.7) | 83 (64.3) | |
| 70–79 | 4 | 21 (10.6) | 9 (13.0) | 12 (9.3) | |
| 80+ | 6 | 6 (3.0) | 0 (0.0) | 6 (4.7) | |
| BMI < 18.5 kg/m2 | 2 | 25(12.6) | 16 (12.4) | 9 (13.0) | 0.898 |
| FEV1, % predicted | 0.204 | ||||
| >80 | 0 | 108 (54.5) | 34 (49.3) | 74 (57.4) | |
| 50–80 | 1 | 70 (35.4) | 27 (39.1) | 43 (33.3) | |
| 30–49 | 2 | 18 (9.1) | 6 (8.7) | 12 (9.3) | |
| <30 | 3 | 2 (1.0) | 2 (2.9) | 0 (0.0) | |
| Hospital admission before study within two years | 5 | 16 (8.1) | 7 (10.1) | 9 (7.0) | 0.438 |
| Exacerbations before study within two years ≥ 3 | 2 | 52 (26.3) | 28 (40.6) | 24 (18.6) | 0.002 |
| MRC dyspnea score | 0.321 | ||||
| 0 | 0 | 197 (99.5) | 68 (98.6) | 129(100.0) | |
| 1–2 | 2 | 1 (0.5) | 1 (1.4) | 0 (0.0) | |
| ≥3 | 3 | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Pseudomonas colonization | 3 | 60 (30.3) | 22 (31.9) | 38 (29.5) | 0.725 |
| Colonization with other organisms | 1 | 137 (69.2) | 69 (100.0) | 68 (52.7) | < 0.001 |
| ≥ 3 lobes involved or cystic bronchiectasis | 1 | 84 (42.4) | 36 (52.2) | 48 (37.2) | 0.045 |
| Total BSI score | 26 | 5 [3–8] | 6 [4–8] | 4 [2–7] | 0.002 |
Data are shown as count (percentile) or median [interquartile range] unless specified otherwise. Abbreviations: BMI, Body Mass Index; FEV1, forced expiratory volume in one second; mMRC, modified Medical Research Council dyspnea scale; BSI, bronchiectasis severity index