Table 4.

Factors associated with the incidence rate of mild exacerbation^* in bronchiectasis patients

Variables	Unadjusted IRR	P	Adjusted IRR	P
H. influenzae colonization†	1.63 [1.08–2.44]	0.019	1.54 [1.06–2.24]	0.023
P. aeruginosa colonization†	2.04 [1.38–3.03]	< 0.001	1.70 [1.12–2.56]	0.012
Bacteria other than H. influenzae and P. aeruginosa colonization	1.90 [1.27–2.84]	0.002	1.31 [0.86–1.99]	0.208
BMI (kg/m2)	0.93 [0.88–0.99]	0.023	0.96 [0.91–1.02]	0.190
Chronic obstructive pulmonary disease	1.85 [1.18–2.91]	0.008	1.03 [0.67–1.58]	0.896
Asthma	1.71 [1.02–2.86]	0.041	1.77 [1.10–2.85]	0.019
Hospitalization history within two years	2.25 [1.22–4.14]	0.009	1.52 [0.86–2.66]	0.148
Involvement ≥ 3 lobes	2.50 [1.69–3.68]	< 0.001	1.72 [1.14–2.57]	0.009

^*Mild exacerbation refers to an outpatient prescription of oral antibiotics due to exacerbation. ^†Colonization was defined as when any type of bacteria was detected at least once from respiratory specimen culture during routine practice. Data are shown as median [interquartile range] unless specified otherwise. Abbreviations: IRR, incidence rate ratio; BMI, Body Mass Index

Abbreviations: ICD, International Classification of Diseases; CT, computed tomography; NTM-PD, Non-tuberculous mycobacterial pulmonary disease