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. 2023 Dec 29;18:8113–8130. doi: 10.2147/IJN.S434579

Figure 1.

Figure 1

Synergistic antibacterial effect of AgNPs and ebselen on planktonic P. gingivalis owing to intracellular ROS increase. (A and B) CFU counting results of live bacteria after treatment with various concentrations of AgNPs and ebselen for 24 h; (C–E) Inhibitory effect of AgNPs and ebselen on P. gingivalis growth after treatment for 24, 48, and 72 h, respectively; (F) Representative fluorescence images of ROS levels in P. gingivalis after being treated with AgNPs and ebselen for 2 h (scale bars: 20 μm); (G) The mean fluorescence intensities of ROS levels in P. gingivalis; (H) Schematic diagram about the potential antibacterial mechanism of AgNPs and ebselen; created with BioRender.com. Data were presented as the mean ± SD. Compared with the control group, *P < 0.05, ***P < 0.001. Compared with the group with the same concentration of AgNPs, #P < 0.05, ##P < 0.01, ###P < 0.001.