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. 2023 Dec 29;18:8113–8130. doi: 10.2147/IJN.S434579

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© 2023 Liang et al.

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Cell viability and intracellular ROS levels of HGFs treated with AgNPs and ebselen. (A) Cell viability of HGFs treated with AgNPs and ebselen; (B) Intracellular ROS levels of HGFs in treatment with AgNPs and ebselen for 6 and 24 h; (C) Fluorescence images were taken at 24 h (scale bars: 100 μm), and (D) the mean fluorescence intensities were measured by image J; (E) The amount of total GSH in HGFs; (F) TrxR activities in HGFs; (G) Expression of SOD2 in HGFs; (H) The schematic illustration of the effect of AgNPs and ebselen on anti-oxidative system; created with BioRender.com. Data were presented as the mean ± SD. Compared with the control group, **P < 0.01, ***P < 0.001. Compared with the group with the same concentration of AgNPs, ^##P < 0.01, ^###P < 0.001.