Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 2;43:9. doi: 10.1186/s13046-023-02910-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 4 — CY12-RP2 suppresses the invasion and migration of melanoma cells via blocking Wnt/β-catenin pathway. A The effect of CY12-RP2 on the colony formation of melanoma cell lines. B The colony formation statistical analysis. C Effects of CY12-RP2 on the migratory capacity of melanoma cell lines were analyzed by wound healing assay. The power field scale bar, 100 μm. D Statistical analysis was performed to determine the migrated distance. E Effects of CY12-RP2 on the invasive ability of melanoma cell lines were analyzed by transwell assays. The power field scale bar, 100 μm. F Statistical analysis was performed to determine the number of invaded cells. G The analysis of CY12-RP2 on EMT and apoptosis signaling pathways by using Western blot assay. Data are presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001 versus control