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. 2024 Jan 2;25:6. doi: 10.1186/s13063-023-07889-7

Table 1.

Composition of human spinal fluid and solutions used in neurosurgery

Component Normal human CSF ACF NS LR
Na+ (mEq/L) 145 145 154 130
K+ (mEq/L) 2.8 2.8 0 4
Mg2+ (mEq/L) 2.2 2.2 0 0
Ca2+ (mEq/L) 2.3 2.3 0 3
Cl (mEq/L) 111.9 129 154 109
P (mmol/L) 1.1 1.1 0 0
HCO3− (mEq/L) 23.1 23.1 0 0
Lactate (mEq/L) 0 0 0 28
Glucose (g/L) 0.61 0.61 0 0
Osmolality ratio ≈1 ≈1 1 ≈0.9
pH 7.307 ≈7.3 ≈6.3 ≈6.7

Abbreviations: CSF cerebrospinal fluid, ACF artificial cerebrospinal fluid, NS normal saline, LR lactated Ringer’s solution