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. 2024 Jan 2;25:24. doi: 10.1186/s12891-023-07142-x

Table 1.

Definition of periprosthetic joint infection

Diagnostic Criteria Concrete Contents
Major Criteria 1) Two positive periprosthetic cultures with phenotypically identical organisms.
2) A sinus tract communicating with the joint.
Minor Criteria 1) Elevated serum C-reactive protein (CRP) AND erythrocyte sedimentation rate (ESR);
2) Elevated synovial fluid white blood cell (WBC) count OR + + change on leukocyte esterase test strip;
3) Elevated synovial fluid polymorphonuclear neutrophil percentage (PMN%);
4) Positive histological analyses of periprosthetic tissue;
5) A single positive culture.

According to the MSIS criteria, PJI is diagnosed when a patient has one of the two major criteria or three of the five minor criteria