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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Nat Cell Biol. 2023 Oct 9;25(11):1616–1624. doi: 10.1038/s41556-023-01250-5

Extended Data Fig. 4. SLC25A38 does not contribute to CoQ biosynthesis.

Extended Data Fig. 4

a, Normalized PPHB abundance in hem25Δ cells expressing Hem25p-FLAG or SLC25A38. (mean ± SD, n = 3 biologically independent samples) b, Relative lipid abundances in hem25Δ yeast compared to WT versus statistical significance with CoQ10 and the CoQ10 biosynthetic intermediate demethoxy-coenzyme Q (DMQ10,) highlighted. c, Relative protein abundance SLC25A38KO cells compared to WT cells versus statistical significance with CoQ-related (COQ3-COQ9) and OxPhos-related proteins highlighted. For panels (b) and (c), raw lipidomic and proteomic data, respectively, from the MITOMICS resource46 are displayed as the mean from three independent samples with two-sided Welch’s t-test used. Source numerical data are available in source data.