Table 2:
GO analysis of significantly reduced proteins.
| GO cellular component | # of genes in H. sapiens reference list |
# of genes in dataset |
expected frequency |
fold enrichment |
raw p value | FDR |
|---|---|---|---|---|---|---|
| collagen type IV trimer (GO:0005587) | 7 | 3 | 0.01 | > 100 | 8.03E-07 | 1.49E-04 |
| basement membrane collagen trimer (GO:0098651) | 9 | 3 | 0.02 | > 100 | 1.47E-06 | 2.14E-04 |
| collagen network (GO:0098645) | 9 | 3 | 0.02 | > 100 | 1.47E-06 | 2.00E-04 |
| network-forming collagen trimer (GO:0098642) | 9 | 3 | 0.02 | > 100 | 1.47E-06 | 1.87E-04 |
| complex of collagen trimers (GO:0098644) | 22 | 4 | 0.04 | 93.59 | 1.76E-07 | 3.59E-05 |
| basement membrane (GO:0005604) | 101 | 7 | 0.2 | 35.67 | 1.43E-09 | 4.88E-07 |
| collagen trimer (GO:0005581) | 88 | 5 | 0.17 | 29.25 | 9.70E-07 | 1.52E-04 |
| collagen-containing extracellular matrix (GO:0062023) | 434 | 15 | 0.84 | 17.79 | 2.26E-15 | 4.62E-12 |
| extracellular matrix (GO:0031012) | 575 | 16 | 1.12 | 14.32 | 5.60E-15 | 3.82E-12 |
| external encapsulating structure (GO:0030312) | 576 | 16 | 1.12 | 14.3 | 5.75E-15 | 2.94E-12 |