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Pharmacokinetic results of CHIR99021 in plasma, liver, and retina when administered via i.p.
| CHIR99021, 25 mpk IP | ||||||
|---|---|---|---|---|---|---|
| Plasma | Liver* | Retina | ||||
| Time (min) | Ave Conc (ng/mL) |
Std Dev | Ave Conc (ng/g) |
Std Dev | Ave Conc (ng/g) |
Std Dev |
| 30 | 9250 | 2236 | 33337 | 3820 | 527 | 244 |
| 180 | 490 | 128 | 4681 | 1084 | 434 | 98 |
| 360 | 41 | 44 | 1165 | 692 | 148 | 24 |
| 960 | 0.3 | 0.0 | 6.1 | 3.7 | 41 | 14 |
| 1440 | 0.4 | 0.2 | 5.2 | 5.7 | 61 | 31 |
