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A) Survival outcomes in the first 1000 days (d) for 50 patients with BFB(+) but no ecDNA amplifications (n=50) in their tumors compared to outcomes for ecDNA(+) patients (n=171). P-Value = 0.02 with log rank test.
B) Maximum copy number and amplicon complexity scores for BFB amplicons sampled from Barrett’s esophagus (non-EAC) compared to esophageal adenocarcinoma (EAC) patients.
