Table 4.
Mortality by Baseline CSF Protein Levels
| CSF Protein < 100 mg/dL | CSF Protein ≥ 100 mg/dL | P-value | ||
|---|---|---|---|---|
|
| ||||
| Deaths within 2 Weeks | No. Patients | 641 | 249 | |
| No. (%) with Event | 159 (25) | 49 (20) | ||
| Hazard Ratio (95% CI) | ||||
| Unadjusted | 1.30 (0.95 – 1.80) | REF | 0.10 | |
| Adjusted1 | 1.15 (0.80 – 1.67) | REF | 0.45 | |
| Deaths within 18 Weeks | No. Patients | 641 | 249 | |
| No. (%) with Event | 278 (43) | 86 (35) | ||
| Hazard Ratio (95% CI) | ||||
| Unadjusted | 1.34 (1.05 – 1.70) | REF | 0.02 | |
| Adjusted1 | 1.24 (0.94 – 1.64) | REF | 0.13 | |
1
Adjusted for Baseline CSF quantitative culture log10 CFU/mL, Glasgow Coma Scale, CSF White Cell, Baseline Opening Pressure, and Seizures