[Preprint]. 2023 Dec 11:2023.12.11.23299806. [Version 1] doi: 10.1101/2023.12.11.23299806

Table 1.

Demographic characteristics of the Slovenia memory clinic cohort

	SCD	Non-AD MCI	AD-MCI	AD-Dementia
Sample size	24	22	41	62
Age, y	62.76 ± 9.82^c,d	67.67 ± 13.07^c,d	75.46 ± 5.71^a,b	75.22 ± 7.46^a,b
Sex, F, n (%)	15/26 (57.7%)	12/22 (54.6%)	26/41 (63.4%)	39/62 (62.9%)
MMSE	28 (24–29)	25 (24.8– 26)	27 (25–29)	21 (17–25)^a,c
CSF Aβ42, pg/ml	1270 (1112–1456)^c,d	1341 (1082–1489)^c,d	696 (606.5–949.5)^a,b	623.5 (550–751.8)^a,b
CSF Aβ42/Aβ40 ratio	1.33 (0.1–0.15)^c,d	0.115 (0.11–0.13)^c,d	0.061 (0.49–0.07)^a,b	0.048 (0.038–0.058)^a,b
CSF total-tau, pg/ml	196 (159.3–277)^c,d	231 (198.3–304.8)^c,d	391 (333–584.5)^a,b,d	815 (645–1090)^a,b,c
CSF p-tau181 (Innotest), pg/ml	38 (31.5–46)^c,d	43.5 (37.5–50.3)^c,d	64 (55–101.5)^a,b,d	111 (92.3–140.5)^a,b,c
Plasma p-tau212, pg/ml	1.750 (0.9–2.8)^c,d	1.850 (1.3–3.6)^c,d	3.4 (2–5)^a,b,d	5.9 (4–7.8)^a,b,c
Plasma p-tau217, pg/ml	1.7 (0.8–3)^c,d	2.1 (1.4–3.8)^c,d	5.1 (3.3–7.8)^a,b,d	8.1 (5.9–10.6)^a,b,c

– Statistically different from SCD

– Statistically different from non-AD MCI

– Statistically different from AD-MCI

– Statistically different from AD-Dementia