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[Preprint]. 2023 Dec 14:2023.12.12.23299878. [Version 1] doi: 10.1101/2023.12.12.23299878

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Figure 2: — Robustness assessment of Aβ42/40 ratio for predicting amyloid PET imaging results. A) Densities of plasma Aβ42/40 ratio by LC-MS/MS in ADRC cohort with and without 10% bias (22% total, upper plot) and 2% measured bias (lower plot) added. B) Scatterplots of Aβ42 and Aβ40 to illustrate proximity to cutoffs defining indeterminate risk and scatterplots of Aβ42/40 ratio with and without 10% CV added noise (upper plot) and 6% added CV (measured) noise (lower plot).

Figure 2: — Robustness assessment of Aβ42/40 ratio for predicting amyloid PET imaging results. A) Densities of plasma Aβ42/40 ratio by LC-MS/MS in ADRC cohort with and without 10% bias (22% total, upper plot) and 2% measured bias (lower plot) added. B) Scatterplots of Aβ42 and Aβ40 to illustrate proximity to cutoffs defining indeterminate risk and scatterplots of Aβ42/40 ratio with and without 10% CV added noise (upper plot) and 6% added CV (measured) noise (lower plot).