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[Preprint]. 2023 Dec 13:rs.3.rs-3728259. [Version 1] doi: 10.21203/rs.3.rs-3728259/v1

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Scored cellularity of low grade CSA and dedifferentiated CSA. The cellularity of monolayer cultures (2D), spheroids (3D) and tumors were evaluated according to pathologic criterion. Cellularity were semi-quantitatively divided into five intervals, from 0–20% to 80–100% and scored correspondingly as level 1 to 5. The low grade and dedifferentiated CSA groups were scored separately. *p < 0.05, **P < 0.001.