Table 2.
Carrier frequencies of the CFTR F508del allele in individuals with severe COVID-19 who survived at the time of hospital release vs. those who died with COVID-19, and meta-analysis p-value of association with COVID-19 outcome. The p-value of association, corrected for multiple testing using the correction method of Benjamini-Holm (pFDR), was obtained from inverse-weighted fixed effects meta-analysis as detailed in Methods.
| Italy | Spain | |||
|---|---|---|---|---|
| survived | died | survived | died | |
| total | 811 | 152 | 812 | 154 |
| wt/wt | 796 | 151 | 796 | 153 |
| wt/F508del5 | 15 | 1 | 16 | 1 |
| carrier frequency, % | 2.09 | 0.66 | 1.97 | 0.65 |
| Meta-analysis | p = 0.178; pFDR = 1 | |||