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. 2023 Dec;33(12):2029–2040. doi: 10.1101/gr.278070.123

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© 2023 Harvey et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

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Figure 6. — Comparison of precision and recall in duplex ONT variant calling versus standard ONT and HiFi. (A) Ratio of log₁₀(1-Statistic) where Statistic is either precision (solid line) or recall (dotted line) of duplex ONT compared to standard ONT sequencing. Anything above the y = 1 line indicates an increase in performance compared to standard ONT and anything below the y = 1 line indicates a decrease in performance compared to standard ONT. (B) Ratio of log₁₀(1-Statistic) where Statistic is either precision (solid line) or recall (dotted line) of duplex ONT compared to HiFi sequencing. Anything above the y = 1 line indicates an increase in performance compared to standard ONT and anything below the y = 1 line indicates a decrease in performance compared to HiFi.