Table 7. Statistical Association between DRPs and hospital-acquired infections among hospitalized stroke patients.
Primary Domain | Causes | Frequency of DRPs (n) | Hospital acquired Infections | p-value | |
---|---|---|---|---|---|
Yes | No | ||||
Drug Selection | Inappropriate drug according to guidelines/formulary | 86 | 80 | 06 | |
Inappropriate combination of drugs, or drugs and herbal medications, or drugs and dietary supplements | 102 | 74 | 28 | 0.000 | |
Appropriate drug according to guidelines/formulary | 62 | 20 | 42 | ||
Dose Selection | Dosage regimen not frequent enough | 132 | 93 | 39 |
0.000 |
Dosage regimen too frequent | 53 | 31 | 22 | ||
Dose timing instructions wrong, unclear or missing | 12 | 06 | 06 | ||
Treatment Duration | Duration of treatment too short | 90 | 63 | 27 | |
Duration of treatment too long | 87 | 67 | 20 | 0.072 | |
Proper Duration of treatment | 73 | 44 | 29 | ||
Dispensing | Prescribed drug not available | 47 | 31 | 16 | 0.003 |
Necessary information not provided or incorrect advice provided | 120 | 80 | 40 | ||
Drug use process | Inappropriate timing of administration or dosing intervals | 110 | 84 | 26 |
0.000 |
Wrong drug administered | 70 | 60 | 10 | ||
Appropriate timing of administration or dosing intervals | 65 | 26 | 39 |
Table adapted from Pharmaceutical Care Network Europe (PCNE) Classification Version 9.1 45